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dbo:abstract
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- La tirosina hidroxilasa o tirosina 3-monooxigenasa (EC 1.14.16.2) es la enzima responsable de catalizar la conversión del aminoácido L-tirosina a dihidroxifenilalanina (DOPA). La DOPA es el precursor de la dopamina, que a su vez es también el precursor de la noradrenalina y la adrenalina. En humanos, la tirosina hidroxilasa es codificada por el gen TH. (es)
- La tirosina hidroxilasa o tirosina 3-monooxigenasa (EC 1.14.16.2) es la enzima responsable de catalizar la conversión del aminoácido L-tirosina a dihidroxifenilalanina (DOPA). La DOPA es el precursor de la dopamina, que a su vez es también el precursor de la noradrenalina y la adrenalina. En humanos, la tirosina hidroxilasa es codificada por el gen TH. (es)
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dbo:arm
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dbo:band
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dbo:chromosome
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dbo:ecNumber
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dbo:hgncid
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dbo:omim
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dbo:symbol
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dbo:wikiPageID
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dbo:wikiPageLength
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dbo:wikiPageRevisionID
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prop-es:altsymbols
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- DYT14; DYT5b; TYH (es)
- DYT14; DYT5b; TYH (es)
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prop-es:autor
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- Coker GT, Vinnedge L, O'Malley KL (es)
- Craig SP, Buckle VJ, Lamouroux A, et al. (es)
- Ginns EI, Rehavi M, Martin BM, et al. (es)
- Grima B, Lamouroux A, Boni C, et al. (es)
- Haycock JW (es)
- Haycock JW, Ahn NG, Cobb MH, Krebs EG (es)
- Joh TH, Park DH, Reis DJ (es)
- Kaneda N, Kobayashi K, Ichinose H, et al. (es)
- Knappskog PM, Flatmark T, Mallet J, et al. (es)
- Kobayashi K, Kaneda N, Ichinose H, et al. (es)
- Le Bourdellès B, Boularand S, Boni C, et al. (es)
- Lüdecke B, Bartholomé K (es)
- Lüdecke B, Dworniczak B, Bartholomé K (es)
- Masserano JM, Weiner N (es)
- Meloni R, Biguet NF, Mallet J (es)
- O'Malley KL, Anhalt MJ, Martin BM, et al. (es)
- Vulliet PR, Woodgett JR, Cohen P (es)
- Zhou QY, Quaife CJ, Palmiter RD (es)
- Coker GT, Vinnedge L, O'Malley KL (es)
- Craig SP, Buckle VJ, Lamouroux A, et al. (es)
- Ginns EI, Rehavi M, Martin BM, et al. (es)
- Grima B, Lamouroux A, Boni C, et al. (es)
- Haycock JW (es)
- Haycock JW, Ahn NG, Cobb MH, Krebs EG (es)
- Joh TH, Park DH, Reis DJ (es)
- Kaneda N, Kobayashi K, Ichinose H, et al. (es)
- Knappskog PM, Flatmark T, Mallet J, et al. (es)
- Kobayashi K, Kaneda N, Ichinose H, et al. (es)
- Le Bourdellès B, Boularand S, Boni C, et al. (es)
- Lüdecke B, Bartholomé K (es)
- Lüdecke B, Dworniczak B, Bartholomé K (es)
- Masserano JM, Weiner N (es)
- Meloni R, Biguet NF, Mallet J (es)
- O'Malley KL, Anhalt MJ, Martin BM, et al. (es)
- Vulliet PR, Woodgett JR, Cohen P (es)
- Zhou QY, Quaife CJ, Palmiter RD (es)
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prop-es:año
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- 1979 (xsd:integer)
- 1983 (xsd:integer)
- 1984 (xsd:integer)
- 1986 (xsd:integer)
- 1987 (xsd:integer)
- 1988 (xsd:integer)
- 1989 (xsd:integer)
- 1990 (xsd:integer)
- 1992 (xsd:integer)
- 1995 (xsd:integer)
- 1996 (xsd:integer)
- 2002 (xsd:integer)
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prop-es:banda
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prop-es:brazo
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prop-es:chembl
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prop-es:cromosoma
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prop-es:doi
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- 101007 (xsd:integer)
- 101016 (xsd:integer)
- 101021 (xsd:integer)
- 101038 (xsd:integer)
- 101073 (xsd:integer)
- 101093 (xsd:integer)
- 101111 (xsd:integer)
- 101159 (xsd:integer)
- 101385 (xsd:integer)
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prop-es:ecNumber
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prop-es:ecnumber
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prop-es:geneatlasImage
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- PBB_GE_TH_208291_s_at_tn.png (es)
- PBB_GE_TH_208291_s_at_tn.png (es)
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prop-es:hgncid
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prop-es:homologene
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prop-es:hsEnsembl
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- ENSG00000180176 (es)
- ENSG00000180176 (es)
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prop-es:hsEntrezgene
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prop-es:hsGenlocChr
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prop-es:hsGenlocDb
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prop-es:hsGenlocEnd
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prop-es:hsGenlocStart
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prop-es:hsRefseqmrna
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- NM_000360 (es)
- NM_000360 (es)
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prop-es:hsRefseqprotein
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- NP_000351 (es)
- NP_000351 (es)
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prop-es:hsUniprot
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prop-es:mmEnsembl
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- ENSMUSG00000000214 (es)
- ENSMUSG00000000214 (es)
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prop-es:mmEntrezgene
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prop-es:mmGenlocChr
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prop-es:mmGenlocEnd
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prop-es:mmGenlocStart
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prop-es:mmRefseqmrna
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- NM_009377 (es)
- NM_009377 (es)
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prop-es:mmRefseqprotein
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- NP_033403 (es)
- NP_033403 (es)
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prop-es:mmUniprot
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prop-es:name
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- Tirosina hidroxilasa (es)
- Tirosina hidroxilasa (es)
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prop-es:número
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- 1 (xsd:integer)
- 2 (xsd:integer)
- 3 (xsd:integer)
- 6 (xsd:integer)
- 7 (xsd:integer)
- 10 (xsd:integer)
- 15 (xsd:integer)
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- 20 (xsd:integer)
- 22 (xsd:integer)
- 6114 (xsd:integer)
- 6523 (xsd:integer)
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prop-es:omim
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prop-es:pmc
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- 48658 (xsd:integer)
- 306135 (xsd:integer)
- 336196 (xsd:integer)
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prop-es:pmid
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- 33381 (xsd:integer)
- 1347949 (xsd:integer)
- 1973163 (xsd:integer)
- 2872999 (xsd:integer)
- 2882428 (xsd:integer)
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prop-es:publicación
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- J. Biol. Chem. (es)
- Nature (es)
- Biochem. Biophys. Res. Commun. (es)
- Hum. Mol. Genet. (es)
- Proc. Natl. Acad. Sci. U.S.A. (es)
- Hum. Genet. (es)
- Nucleic Acids Res. (es)
- Biochemistry (es)
- J. Neurochem. (es)
- Cytogenet. Cell Genet. (es)
- J. Biochem. (es)
- Mol. Cell. Biochem. (es)
- Mol. Neurobiol. (es)
- J. Biol. Chem. (es)
- Nature (es)
- Biochem. Biophys. Res. Commun. (es)
- Hum. Mol. Genet. (es)
- Proc. Natl. Acad. Sci. U.S.A. (es)
- Hum. Genet. (es)
- Nucleic Acids Res. (es)
- Biochemistry (es)
- J. Neurochem. (es)
- Cytogenet. Cell Genet. (es)
- J. Biochem. (es)
- Mol. Cell. Biochem. (es)
- Mol. Neurobiol. (es)
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prop-es:páginas
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- 29 (xsd:integer)
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- 13680 (xsd:integer)
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prop-es:símbolo
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prop-es:título
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- Post-genomic era and gene discovery for psychiatric diseases: there is a new art of the trade? The example of the HUMTH01 microsatellite in the Tyrosine Hydroxylase gene. (es)
- Phosphorylation of tyrosine hydroxylase by calmodulin-dependent multiprotein kinase. (es)
- Localization of the human tyrosine hydroxylase gene to 11p15: gene duplication and evolution of metabolic pathways. (es)
- Isolation of a full-length cDNA clone encoding human tyrosine hydroxylase type 3. (es)
- Frequent sequence variant in the human tyrosine hydroxylase gene. (es)
- A single human gene encoding multiple tyrosine hydroxylases with different predicted functional characteristics. (es)
- Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. (es)
- Isolation and characterization of the human tyrosine hydroxylase gene: identification of 5' alternative splice sites responsible for multiple mRNAs. (es)
- Expression of human tyrosine hydroxylase cDNA in invertebrate cells using a baculovirus vector. (es)
- Phosphorylation of tyrosine hydroxylase in situ at serine 8, 19, 31, and 40. (es)
- ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. (es)
- Tyrosine hydroxylase regulation in the central nervous system. (es)
- Characterization of rat and human tyrosine hydroxylase genes: functional expression of both promoters in neuronal and non-neuronal cell types. (es)
- Structure of the human tyrosine hydroxylase gene: alternative splicing from a single gene accounts for generation of four mRNA types. (es)
- Analysis of the 5' region of the human tyrosine hydroxylase gene: combinatorial patterns of exon splicing generate multiple regulated tyrosine hydroxylase isoforms. (es)
- Isolation of a novel cDNA clone for human tyrosine hydroxylase: alternative RNA splicing produces four kinds of mRNA from a single gene. (es)
- A point mutation in the tyrosine hydroxylase gene associated with Segawa's syndrome. (es)
- Recessively inherited L-DOPA-responsive dystonia caused by a point mutation in the tyrosine hydroxylase gene. (es)
- Direct phosphorylation of brain tyrosine hydroxylase by cyclic AMP-dependent protein kinase: mechanism of enzyme activation. (es)
- Post-genomic era and gene discovery for psychiatric diseases: there is a new art of the trade? The example of the HUMTH01 microsatellite in the Tyrosine Hydroxylase gene. (es)
- Phosphorylation of tyrosine hydroxylase by calmodulin-dependent multiprotein kinase. (es)
- Localization of the human tyrosine hydroxylase gene to 11p15: gene duplication and evolution of metabolic pathways. (es)
- Isolation of a full-length cDNA clone encoding human tyrosine hydroxylase type 3. (es)
- Frequent sequence variant in the human tyrosine hydroxylase gene. (es)
- A single human gene encoding multiple tyrosine hydroxylases with different predicted functional characteristics. (es)
- Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development. (es)
- Isolation and characterization of the human tyrosine hydroxylase gene: identification of 5' alternative splice sites responsible for multiple mRNAs. (es)
- Expression of human tyrosine hydroxylase cDNA in invertebrate cells using a baculovirus vector. (es)
- Phosphorylation of tyrosine hydroxylase in situ at serine 8, 19, 31, and 40. (es)
- ERK1 and ERK2, two microtubule-associated protein 2 kinases, mediate the phosphorylation of tyrosine hydroxylase at serine-31 in situ. (es)
- Tyrosine hydroxylase regulation in the central nervous system. (es)
- Characterization of rat and human tyrosine hydroxylase genes: functional expression of both promoters in neuronal and non-neuronal cell types. (es)
- Structure of the human tyrosine hydroxylase gene: alternative splicing from a single gene accounts for generation of four mRNA types. (es)
- Analysis of the 5' region of the human tyrosine hydroxylase gene: combinatorial patterns of exon splicing generate multiple regulated tyrosine hydroxylase isoforms. (es)
- Isolation of a novel cDNA clone for human tyrosine hydroxylase: alternative RNA splicing produces four kinds of mRNA from a single gene. (es)
- A point mutation in the tyrosine hydroxylase gene associated with Segawa's syndrome. (es)
- Recessively inherited L-DOPA-responsive dystonia caused by a point mutation in the tyrosine hydroxylase gene. (es)
- Direct phosphorylation of brain tyrosine hydroxylase by cyclic AMP-dependent protein kinase: mechanism of enzyme activation. (es)
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prop-es:width
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dct:subject
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rdf:type
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rdfs:comment
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- La tirosina hidroxilasa o tirosina 3-monooxigenasa (EC 1.14.16.2) es la enzima responsable de catalizar la conversión del aminoácido L-tirosina a dihidroxifenilalanina (DOPA). La DOPA es el precursor de la dopamina, que a su vez es también el precursor de la noradrenalina y la adrenalina. En humanos, la tirosina hidroxilasa es codificada por el gen TH. (es)
- La tirosina hidroxilasa o tirosina 3-monooxigenasa (EC 1.14.16.2) es la enzima responsable de catalizar la conversión del aminoácido L-tirosina a dihidroxifenilalanina (DOPA). La DOPA es el precursor de la dopamina, que a su vez es también el precursor de la noradrenalina y la adrenalina. En humanos, la tirosina hidroxilasa es codificada por el gen TH. (es)
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rdfs:label
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- Tirosina hidroxilasa (es)
- Tirosina hidroxilasa (es)
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owl:sameAs
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prov:wasDerivedFrom
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foaf:isPrimaryTopicOf
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